Ethylene oxide is not an acute health hazard but can be harmful if continually ingested over time. Safety Information. Recommended use and restrictions on use. SWIMMING POOL..1. Unfortunately, EtO possesses several physical and health hazards that merit special attention. TWENTY. Ethylene oxide is a colorless and flammable gas with a faintly sweet odor. (1959)]. Ethylene Oxide SAFETY DATA SHEET Effective Date: 10-1-2013 Revision: C ARC Language: EN Page 1 of 17 1. Notice to Interested Parties Proposition 65 Listed Chemicals Affected by Hazard Communications Standard Amendments; Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead UN 1040 Ethylene Oxide UN 1040 Ethylene Oxide Labels 2.3, 2.1 Hazard number 263 Packing Instruction P200 IMDG Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Packing Instruction P200 EmS FD,SU IATA Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Recommended: Chemical intermediate for production of No smoking. Avoid breathing gas. Ethylene oxide monitoring data from July through October 2019 show little change over the previous nine months. * Skin contact with liquid Ethylene can cause frostbite. Provides a summary source of information of all potential and most … All electrical equipment should be non-sparking or explosion proof. Wear protective clothing. Ethylene Oxide Health and fire hazards of ethylene oxide How you can be exposed to ethylene oxide How we control Many workers are unaware of the potential hazards in their work environment, which makes them more vulnerable to injury. Multiple studies have shown that EO increases the risk of several types of cancer. Reproductive Hazard Ethylene Oxide may be a TERATOGEN in humans since it There is limited evidence that Ethylene Oxide causes spontaneous abortions. Multiple studies have shown that EO increases the risk of several types of cancer. It is a cyclic ether and the simplest epoxide: a three-membered ring consisting of one oxygen atom and two carbon atoms. Exposure to ethylene oxide may cause headache, nausea, vomiting, diarrhea, breathing difficulty, drowsiness, weakness, exhaustion, eye and skin burns, frostbite, and reproductive effects. Explosions occur , although infrequently, from the combination of ethylene oxide and alcohols or mercaptans, [Chem. Ethylene Oxide may damage the developing fetus. Soc. Provides links and references to additional resources related to exposures to ethylene oxide. It dissolves easily in water.Ethylene oxide is a man-made chemical that is used primarily to make ethylene glycol (a chemical used to make antifreeze and polyester). Ethylene oxide. ETHYLENE OXIDE IN THE HUMAN BODY. Citing the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention (CDC), the Washington Department of Labor & Industries cautions health care employers and others who sterilize respirators for reuse that ethylene oxide is a carcinogen that “has been linked to neurologic dysfunction and may cause other harmful effects” to the eyes, […] Ethylene oxide is a flammable gas with a somewhat sweet odor. Alternative chemicals or processes have, in themselves, serious limitations or health hazards. The Ethylene Oxide Panel supports policies based on the best available science and research on health, safety and environmental issues arising from the production, use, storage, transportation and disposal of ethylene oxide. (2) • Dermal or ocular contact with solutions of ethylene oxide has caused irritation of the skin and eyes in humans. Ethylene Oxide. IDENTIFICATION OF THE SUBSTANCE OR MIXTURE AND OF THE SUPPLIER 1.1. News 20:1318(1942)]. Ethylene Oxide Other means of identification. History of Ethylene Oxide . Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Maximize Your Spirometry Screening and Surveillance Resources, Protect Yourself - Spirometry Breathing Test, OSHA's Small Business Guide for Ethylene Oxide, Severe Storm and Flood Recovery Assistance. Ethylene oxide may severely irritate or burn mucous membranes and moist skin. Any potential association between ethylene oxide and cancer is linked only to chronic exposure. SWIMMING POOLS. It is also used as a fumigant in certain agricultural products and as a sterilant for medical equipment and supplies. May 1994. Provides references that aid in recognizing and evaluating ethylene oxide hazards in the workplace. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Ethylene Oxide (EtO): Evidence of Carcinogenicity, Special Occupational Hazard Review With Control Recommendations: Use of Ethylene Oxide as a Sterilant in Medical Facilities, International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcinogenic Risks for Humans: Ethylene Oxide, International Chemical Safety Cards (ICSC), Severe Storm and Flood Recovery Assistance. At very low The EPA classified the chemical as a human carcinogen in 2016. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. If allergy GHS product identifier. NIOSH REL: <0.1 ppm (<0.18 mg/m 3) TWA, 5 ppm (9 mg/m 3) CEILING, 10-minutes/day; NIOSH considers ethylene oxide to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. Exposures to ethylene oxide are addressed in specific OSHA standards for general industry, maritime, and construction. SWIMMING POOL..1. Ethylene oxide stored in the liquid state can be maintained free of explosion hazard in the gaseous phase by the introduction of nitrogen at sufficient pressure. In general, with higher levels of exposure to the chemical, more severe effects will occur. EtO is both flammable and highly reactive. Ethylene oxide (EtO) is produced in large volumes and is primarily used as an intermediate in the production of several industrial chemicals, the most notable of which is ethylene glycol. Eng. Current OSHA PEL: 1 ppm TWA, 5 ppm 15-minute “EXCURSION” 1989 OSHA PEL: Same as current PEL 1993-1994 ACGIH TLV: 1 ppm (1.8 mg/m 3) TWA, A2 CAS number: 75–21–8 NIOSH REL: <0.1 ppm (<0.18 mg/m 3) TWA, 5 ppm (9 mg/m 3) CEILING, 10-minutes/day; NIOSH considers ethylene oxide to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. TWENTY. Chronic exposure has been associated with the occurrence of cancer, reproductive effects, mutagenic changes, neurotoxicity, and sensitization. It has been determined to be carcinogenic to humans. It dissolves easily in water, alcohol, and most organic solvents. Flammable Properties: EXTREMELY FLAMMABLE GAS. M aterial Safety Data Sheet Issue Date: Aug. 01, 2013 ETHYLENE OXIDE Supercedes: Sep. 01, 2011 Page 2 of 12 GHS Category table for reference: Study/hazard statement Category 1 Category 2 Category 3 Category 4 Category 5 ONE. Ethylene Oxide Section 2. The first study to establish a potential link between ethylene oxide and cancer was published in 1948, and in it, researchers found that ethylene oxide is a mutagen. * Exposure to Ethylene can cause headache, dizziness, fatigue, lightheadedness, confusion and unconsciousness. Ethylene oxide (also known as ETO or oxirane) is a flammable gas with a somewhat sweet odor. Ethylene Oxide may damage the developing fetus. Provides references that aid in preventing and controlling exposures to ethylene oxide. Ethylene Oxide. Ethylene oxide is produced in large volumes and is used to make other chemicals, especially ethylene glycol, a chemical used to make antifreeze and polyester. View 301 Chapter 6 MSDS EtOKit.ppt from CHEMICAL 434 at Universiti Teknologi Mara. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. What are fire hazards and extinguishing media for ethylene oxide? Other Effects Ethylene Oxide may cause a skin allergy. Ethylene Oxide may damage the testes (male reproductive glands). Safety data sheet Ethylene Oxide Creation date : 28.01.2005 Version : 2.0 DE / E SDS No. Wear protective gloves. Journal of Hazardous Materials 2005 , 118 (1-3) , 19-34. New Jersey Department of Health and Senior Services, Hazardous Substance Fact Sheet, (Revised November 2009). Ethylene oxide is industrially produce… ETHYLENE OXIDE IN THE HUMAN BODY. Flammable Properties: EXTREMELY FLAMMABLE GAS. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. * Ethylene is a HIGHLY FLAMMABLE and REACTIVE chemical and a DANGEROUS FIRE and EXPLOSION HAZARD. Ethylene Oxide may damage the testes (male reproductive glands). OLYMPIC SIZE. GHS Hazard Statements: H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H331 (100%): Toxic if inhaled [Danger Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases. Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in the environment is … Wear eye or face protection. Symbol GHS02,GHS04,GHS05,GHS06,GHS08. Ethylene oxide is generally synthesized by chlorohydrine process and direct oxidation of ethylene with air, catalyzed by silver(Ag). ONE. Ethylene oxide is expected to volatilize from dry soil surfaces (SRC) based upon a vapor pressure of 1.31X10+3 mm Hg (4). If allergy Other Effects Ethylene Oxide may cause a skin allergy. Environmental Protection Agency (EPA). (2) • Dermal or ocular contact with solutions of ethylene oxide has caused irritation of the skin and eyes in humans. Emergency Life-Support Procedures: Acute exposure to ethylene oxide may require decontamination and life support for the victims. SWIMMING POOLS. Hazard statements (GHS-US) : H220 - EXTREMELY FLAMMABLE GAS H280 - CONTAINS GAS UNDER PRESSURE; MAY EXPLODE IF HEATED H315+H320 - CAUSES SKIN AND EYE IRRITATION Protecting the health and safety of the public is a top priority for the producers and users of ethylene oxide and our industry. • Acute inhalation exposure of workers to high levels of ethylene oxide has resulted in nausea, vomiting, neurological disorders, bronchitis, pulmonary edema, and emphysema. 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